Telomere length could be considered a molecular marker of spermatogenesis and sperm quality and is somewhat related to male fertility potential. Fewer evidence, although promising, is available for oocytes, female (in)fertility, and embryo quality.


Exercise increases telomere length, as well as omega-three fatty acids and vegetables and fruits with high antioxidants. Of recent interest resveratrol from red wine and nicotinamide dinucleotide, available as a supplement can also increase telomere length. Additionally, astragalus root has been shown to increase telomere length in studies.

2015-11-13 Telomere length, stem cells and aging Telomere shortening occurs concomitant with organismal aging, and it is accelerated in the context of human diseases associated with mutations in telomerase, such as some cases of dyskeratosis congenita, idiopathic pulmonary fibrosis and aplastic anemia. People with these diseases, as well as Terc-d … 2020-03-20 2020-09-10 2018-09-09 Analysis of telomere length in human peri pheral blood mononuclear cells reveals that telomere length decreases with increased age in the donor ( 15), reflecting the replicative history of those cells. In several disorders, e.g., Down´s syndrome, ataxia telangiectasia and during HIV infection, accelerated telomere loss has been described, Telomere length (TL) is currently used as an emerging biomarker in understanding the development/progression of hematological malignancies. The absolute quantitative PCR (qPCR) methodology has allowed the study of TL from a variety of mammalian tissues, but it has not been tested for bone marrow (BM) samples.

Telomere length

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Telomere length, a   Nov 13, 2020 Prematurely shortened leukocyte telomere length is associated with IPF and chronic obstructive pulmonary disease (COPD), a disease with  Sep 2, 2020 Thus in the current paper, we review the factors that affect telomere length in human cells focusing on sex that all together with different  Telomere length in humans seems to decrease at a rate of 24.8–27.7 base pairs per year [12,13]. Telomere length, shorter than the average telomere length for a   Oct 22, 2020 We investigated potential associations between telomere length and somatic copy number alterations (SCNAs), as SCNAs are associated with  Jan 2, 2020 Several studies reported shortening of sperm telomeres associated with infertility. Thus, sperm telomere length can be used as biomarker for the  Feb 26, 2018 Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres Nov 4, 2020 Lifestyle is an important determinant of telomere length and telomerase function – this may explain how we age more, or less, than others through  Telomerase is able to maintain telomere length in germline cells, but continuous shortening of telomeres is a consequence of cell division in most somatic cells  Does telomere length matter? Some people claim that telomere shortening is a major contributor to the aging process and development of disease.

Z Niu, L Mu, X Wen, Q Pu. Annals of Epidemiology  of environmental exposures in children delivered preterm; telomere length, inflammation and lung function (paper I), viral respiratory infections and cellular  We also expected that telomere length would be shorter in birds with higher metabolites are linked to hatching success and telomere length in breeding  Telomeres in sperm not only change with age and affect offspring telomere length, but also have a direct effect on sperm performance. Swim-up experiments for  Regardless of their birthplace, city-raised chicks' telomeres were 11% shorter than Telomere length is thought to reflect aging at the cellular level, and their  Exploring the causal pathway from telomere length to coronary heart disease: a network Mendelian randomization study. Y Zhan, IK Karlsson, R Karlsson,  Telomere length and physical performance among older people-The Helsinki Birth Cohort Study.Mechanisms of ageing and development.

May 25, 2017 Telomere length. “People with shorter telomeres have a higher risk of pulmonary fibrosis and aplastic anemia, and, if they're smokers, they may 

In this review, the human evidence that telomere length is a biomarker of aging is evaluated. Although telomere length is implicated in cellular aging, the evidence suggesting telomere length is a biomarker of aging in humans Researchers are still unsure whether telomere length is just a marker of aging, like gray hair or wrinkles, or if it’s an active factor in whether a person is more likely to have a disease like Alzheimer’s or die.

May 31, 2020 We tested whether rapid growth is achieved at the expense of telomere length by comparing crickets reared at 23°C with their siblings reared at 

Telomere length

European Respiratory Journal 55  LIBRIS titelinformation: Telomere length as prognostic parameter in chronic lymphocytic leukemia [Elektronisk resurs] / Pawel Grabowski. Svensk översättning av 'telomere length' - engelskt-svenskt lexikon med många fler översättningar från engelska till svenska gratis online. L. A. Tucker, “Caffeine Consumption and Telomere Length in Men and Women of the National Health and Nutrition Examination Survey (NHANES),” Nutrition  av U Svenson · 2011 · Citerat av 125 — There is a considerable heterogeneity in blood cell telomere length (TL) for individuals of similar age and recent studies have revealed that TL  Swedish University dissertations (essays) about TELOMERE LENGTH. Search and download thousands of Swedish university dissertations.

2020-10-09 · Telomere length impacts women’s longevity. Recent research makes it evident that women bearing birth later in their life may increase their life span. The research on menopause enlightens that the life of a woman increases after the birth of her last child. The study was published in the Journal Of The North American Menopause Society (NAMS).
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Telomere length represents our biological age as opposed to our chronological age. Many scientific studies have shown a strong connection between short telomeres and cellular aging.

Blood 2006; 107: 2680-2685.
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A decrease in telomere length in AD brains has been associated with decrease in telomerase expression. // Since caspase-mediated 

Telomere length was quantified by comparing the amount of the telomere amplification product (T) to that of a single-copy gene (S), with amplification of the telomere and single gene proceeding in separate wells or tubes. 2011-01-31 · The amount of telomere sequence in TEL STD A is calculated as: 1.36 × 10 9 × 84 (oligomer length) = 1.18 × 10 8 kb of telomere sequence in TEL STD A. A standard curve is generated by performing the aTL qPCR assay on serial dilutions of TEL STD A (10 -1 [ 1.18 × 10 8] through to 10 -6 [1.18 × 10 3] dilution). 2007-09-17 · Bellon, M. et al. Increased expression of telomere length regulating factors TRF1, TRF2 and TIN2 in patients with adult T-cell leukemia. Int. J. Cancer 119, 2090–2097 (2006). 2011-10-01 · Telomere length is also influenced by gender; telomeres in women are longer when compared to those in men,,. Telomere length shortens with normal aging, life stress, infection and chronic diseases,,,.